Biotechnology
Drug developers by modality or disease area, diagnostics and tools.
Leadership as of 2026-10-27: Lagging. Relative to SPY: 5 sessions +0.6pp, 21 sessions −3.4pp, 63 sessions −1.3pp. Participation 39%; 136 of 157 members eligible.
- 21-session excess -3.4pp
- 63-session excess -3.3pp (robust)
Member companies
- Iovance Biotherapeutics, Inc. (IOVA)
- CareDx, Inc. (CDNA)
- Moderna, Inc. (MRNA)
- Xencor, Inc. (XNCR)
- Absci Corporation (ABSI)
- GRAIL, Inc. (GRAL)
- Halozyme Therapeutics, Inc. (HALO)
- Kodiak Sciences Inc (KOD)
- Verastem, Inc. (VSTM)
- Replimune Group, Inc. (REPL)
- SELLAS Life Sciences Group, Inc (SLS)
- Natera, Inc. (NTRA)
- Exelixis, Inc. (EXEL)
- Twist Bioscience Corporation (TWST)
- Biogen Inc. (BIIB)
- Nurix Therapeutics, Inc. (NRIX)
- Vir Biotechnology, Inc. (VIR)
- Rigel Pharmaceuticals, Inc. (RIGL)
- Spyre Therapeutics, Inc. (SYRE)
- Arcutis Biotherapeutics, Inc. (ARQT)
- Certara, Inc. (CERT)
- ImmunityBio, Inc. (IBRX)
- Kymera Therapeutics, Inc. (KYMR)
- Amgen Inc. (AMGN)
- Schrodinger, Inc. (SDGR)
- Sagimet Biosciences Inc. (SGMT)
- Relay Therapeutics, Inc. (RLAY)
- AbbVie Inc. (ABBV)
- Biohaven Ltd. (BHVN)
- Prime Medicine, Inc. (PRME)
- Roivant Sciences Ltd. (ROIV)
- TG Therapeutics, Inc. (TGTX)
- United Therapeutics Corporation (UTHR)
- Gilead Sciences, Inc. (GILD)
- Myriad Genetics, Inc. (MYGN)
- Protagonist Therapeutics, Inc. (PTGX)
- Viridian Therapeutics, Inc. (VRDN)
- Agios Pharmaceuticals, Inc. (AGIO)
- Regeneron Pharmaceuticals, Inc. (REGN)
- Achieve Life Sciences, Inc. (ACHV)
- Erasca, Inc. (ERAS)
- Vaxcyte, Inc. (PCVX)
- Revolution Medicines, Inc. (RVMD)
- Disc Medicine, Inc. (IRON)
- Novavax, Inc. (NVAX)
- Alkermes plc (ALKS)
- Veracyte, Inc. (VCYT)
- Recursion Pharmaceuticals, Inc. (RXRX)
- Precigen, Inc. (PGEN)
- 4D Molecular Therapeutics, Inc. (FDMT)
- Janux Therapeutics, Inc. (JANX)
- Vertex Pharmaceuticals Incorpor (VRTX)
- Vor Biopharma Inc. (VOR)
- Vericel Corporation (VCEL)
- Inhibrx Biosciences, Inc. (INBX)
- ADMA Biologics Inc (ADMA)
- Kura Oncology, Inc. (KURA)
- Zenas BioPharma, Inc. (ZBIO)
- Travere Therapeutics, Inc. (TVTX)
- Cullinan Therapeutics, Inc. (CGEM)
- Krystal Biotech, Inc. (KRYS)
- Tango Therapeutics, Inc. (TNGX)
- AnaptysBio, Inc. (ANAB)
- Sarepta Therapeutics, Inc. (SRPT)
- Incyte Corporation (INCY)
- Intellia Therapeutics, Inc. (NTLA)
- Candel Therapeutics, Inc. (CADL)
- Immix Biopharma, Inc. (IMMX)
- Summit Therapeutics Inc. (SMMT)
- CRISPR Therapeutics AG (CRSP)
- Neurocrine Biosciences, Inc. (NBIX)
- Arbutus Biopharma Corporation (ABUS)
- CG Oncology, Inc. (CGON)
- Dianthus Therapeutics, Inc. (DNTH)
- IDEAYA Biosciences, Inc. (IDYA)
- BridgeBio Pharma, Inc. (BBIO)
- Damora Therapeutics, Inc. (DMRA)
- Shattuck Labs, Inc. (STTK)
- BioCryst Pharmaceuticals, Inc. (BCRX)
- BioMarin Pharmaceutical Inc. (BMRN)
- Cogent Biosciences, Inc. (COGT)
- Ironwood Pharmaceuticals, Inc. (IRWD)
- Savara, Inc. (SVRA)
- Beam Therapeutics Inc. (BEAM)
- Celldex Therapeutics, Inc. (CLDX)
- Immunovant, Inc. (IMVT)
- Neurogene Inc. (NGNE)
- Praxis Precision Medicines, Inc (PRAX)
- Scholar Rock Holding Corporatio (SRRK)
- Rhythm Pharmaceuticals, Inc. (RYTM)
- Cytokinetics, Incorporated (CYTK)
- Mirum Pharmaceuticals, Inc. (MIRM)
- Denali Therapeutics Inc. (DNLI)
- Dyne Therapeutics, Inc. (DYN)
- MannKind Corporation (MNKD)
- Monopar Therapeutics Inc. (MNPR)
- Stoke Therapeutics, Inc. (STOK)
- Faeth Therapeutics, Inc. (FTH)
- MiMedx Group, Inc (MDXG)
- Vera Therapeutics, Inc. (VERA)
- Arrowhead Pharmaceuticals, Inc. (ARWR)
- PTC Therapeutics, Inc. (PTCT)
- ACADIA Pharmaceuticals Inc. (ACAD)
- Bicara Therapeutics Inc. (BCAX)
- Emergent BioSolutions Inc. (EBS)
- Tyra Biosciences, Inc. (TYRA)
- Madrigal Pharmaceuticals, Inc. (MDGL)
- Solid Biosciences Inc. (SLDB)
- Immunome, Inc. (IMNM)
- uniQure N.V. (QURE)
- Ultragenyx Pharmaceutical Inc. (RARE)
- Corvus Pharmaceuticals, Inc. (CRVS)
- Annexon, Inc. (ANNX)
- Insmed Incorporated (INSM)
- Taysha Gene Therapies, Inc. (TSHA)
- Capricor Therapeutics, Inc. (CAPR)
- Ionis Pharmaceuticals, Inc. (IONS)
- Oric Pharmaceuticals, Inc. (ORIC)
- Celcuity Inc. (CELC)
- Arcus Biosciences, Inc. (RCUS)
- Mineralys Therapeutics, Inc. (MLYS)
- Alnylam Pharmaceuticals, Inc. (ALNY)
- Syndax Pharmaceuticals, Inc. (SNDX)
- Viking Therapeutics, Inc. (VKTX)
- Monte Rosa Therapeutics, Inc. (GLUE)
- REGENXBIO Inc. (RGNX)
- Ardelyx, Inc. (ARDX)
- Nektar Therapeutics (NKTR)
- Olema Pharmaceuticals, Inc. (OLMA)
- ArriVent BioPharma, Inc. (AVBP)
- ARS Pharmaceuticals, Inc. (SPRY)
- Avalo Therapeutics, Inc. (AVTX)
- Aktis Oncology, Inc. (AKTS)
- Hemab Therapeutics Holdings, In (COAG)
- Kailera Therapeutics, Inc. (KLRA)
- First Tracks Biotherapeutics, I (TRAX)
- Allogene Therapeutics, Inc. (ALLO)
- Altimmune, Inc. (ALT)
- Assembly Biosciences, Inc. (ASMB)
- Aura Biosciences, Inc. (AURA)
- BridgeBio Oncology Therapeutics, Inc. (BBOT)
- Cabaletta Bio, Inc. (CABA)
- Crescent Biopharma, Inc. (CBIO)
- CytomX Therapeutics, Inc. (CTMX)
- Design Therapeutics, Inc. (DSGN)
- Editas Medicine, Inc. (EDIT)
- Geron Corporation (GERN)
- Jade Biosciences, Inc. (JBIO)
- Lexeo Therapeutics, Inc. (LXEO)
- Ocugen, Inc. (OCGN)
- Oruka Therapeutics, Inc. (ORKA)
- Ovid Therapeutics Inc. (OVID)
- Prothena Corporation plc (PRTA)
- Palvella Therapeutics, Inc. (PVLA)
- Sana Biotechnology, Inc. (SANA)
- Simulations Plus, Inc. (SLP)
- Vanda Pharmaceuticals Inc. (VNDA)
Themes in this family
- Large-Cap Biopharma: Leading — 21-session vs SPY +6.1pp, participation 75%
- Neuro / CNS: Neutral — 21-session vs SPY −0.2pp, participation 43%
- Molecular Diagnostics: Weakening — 21-session vs SPY +15.9pp, participation 80%
- Immunology & Inflammation: Lagging — 21-session vs SPY −3.6pp, participation 29%
- Rare & Genetic Disease: Lagging — 21-session vs SPY −3.6pp, participation 32%
- RNA Therapeutics: Lagging — 21-session vs SPY −4.2pp, participation 40%
- Oncology: Lagging — 21-session vs SPY −8.2pp, participation 32%
- Gene Therapy: Lagging — 21-session vs SPY −16.6pp, participation 0%
- Targeted Protein Degradation: Tracked (too few stocks for a leadership state) — 21-session vs SPY +2.4pp, participation 67%
- Gene Editing: Tracked (too few stocks for a leadership state) — 21-session vs SPY +1.3pp, participation 67%
- Vaccines: Tracked (too few stocks for a leadership state) — 21-session vs SPY −0.6pp, participation 50%
- Obesity / MASH: Tracked (too few stocks for a leadership state) — 21-session vs SPY −4.7pp, participation 50%
- Specialty Pharma: Tracked (too few stocks for a leadership state) — 21-session vs SPY −10.1pp, participation 0%
- AI Drug Discovery: Exposure tag
- Antiviral Therapeutics: Exposure tag
- Cardiovascular: Exposure tag
- Cell Therapy: Exposure tag
- Drug Delivery Technology: Exposure tag
- Drug-Discovery Simulation Software: Exposure tag
- Ophthalmology Therapeutics: Exposure tag
- Plasma-Derived Biologics: Exposure tag
- Regenerative Medicine: Exposure tag
- Synthetic Biology Tools: Exposure tag